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有髓神经中狭窄近端早期变化的电子显微镜研究。

Electron microscopic study of the early changes proximal to a constriction in myelinated nerve.

作者信息

Logroscino C A, Sanguinetti C, Catalano F

出版信息

Int Orthop. 1980;4(2):121-5. doi: 10.1007/BF00271095.

DOI:10.1007/BF00271095
PMID:7429681
Abstract

An ultrastructural study has been carried out of the changes observed proximal to a nerve constriction in rabbits. The lesion was experimentally produced with a silk ligature. Specimens were examined 24 h after ligation. Significant alterations of the ultra structure were found in sections taken at approximately 1 mm above the constriction. Examination revealed swelling of the nerve fibres due to failure of axoplasmic flow, a marked increase in the number of mitochondria, most of which showed degenerative changes and degenerative changes in the myelin sheath.

摘要

已对家兔神经缩窄近端观察到的变化进行了超微结构研究。该损伤是通过丝线结扎实验性造成的。在结扎后24小时检查标本。在缩窄上方约1毫米处取的切片中发现了超微结构的显著改变。检查发现,由于轴浆流动受阻,神经纤维肿胀,线粒体数量显著增加,其中大多数显示出退行性变化,髓鞘也有退行性变化。

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Proximo-distal movement along the axon of protein synthesized in the perikaryon of regenerating neurons.沿着再生神经元胞核中合成的蛋白质的轴突进行的近端到远端的移动。
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