呋塞米可减少胃酸分泌。
Furosemide reduces gastric acid secretion.
作者信息
Ayalon A, Corcia A, Caplan S R
出版信息
Isr J Med Sci. 1980 Sep-Oct;16(9-10):625-7.
PMID:7429794
Abstract
Furosemide (10(-3) M) reduced acid secretion of isolated fundic mucosa of the guinea pig by 40%, and lowered the short circuit current, carried mainly by Cl- ions, by 49 +/- 2 (SE) %. These effects occurred within seconds of application of the drug to the serosal side of the mucosa and were fully reversible. When the drug was applied to the mucosal side, the same effects were obtained.
摘要
速尿（10⁻³M）使豚鼠离体胃底黏膜的酸分泌减少了40%，并使主要由氯离子携带的短路电流降低了49±2（标准误）%。这些效应在将药物应用于黏膜浆膜侧后数秒内出现，且完全可逆。当将药物应用于黏膜侧时，也获得了相同的效应。
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