Alekseevskikh Iu G
Arkh Patol. 1978;40(12):38-44.
Morphological examinations of the microcirculatory bed of the lungs and pulmonary pleura in 30 fatal cases of cirrhosis of the liver revealed generalized involvement of the blood and lymph vessels. Most significant changes were found in venular and lymphomicrocirculatory parts of the pulmonary pleura as a manifestation of compensatory-adaptative processes directed at retention of the hemodynamic homeostasis of the pulmonary circulation. In the author's opinion, the most important factors causing reactions of the microcirculatory bed of the pulmonary pleura include venous hypervolemia of the pulmonary circulation followed by hypoxia. It is suggested that changes in the vessels of the microcirculatory bed of the lungs and pulmonary pleura in patients with cirrhosis of the liver are an important part of the compensatory-adaptative mechanisms; their disorders cause the development of the right ventricle insufficiency.
对30例肝硬变致死病例的肺和胸膜微循环床进行的形态学检查显示,血管和淋巴管普遍受累。在胸膜的小静脉和微淋巴循环部分发现了最显著的变化,这是旨在维持肺循环血液动力学稳态的代偿适应过程的表现。作者认为,导致胸膜微循环床反应的最重要因素包括肺循环静脉血容量过多,继而出现缺氧。有人提出,肝硬变患者肺和胸膜微循环床血管的变化是代偿适应机制的重要组成部分;它们的紊乱会导致右心室功能不全的发展。