Precordial voltage variation in the normal electrocardiogram.

Intra-individual precordial voltage variation was examined in serial 12 lead electrocardiograms (ECGs) performed at 10 minute and 24 hour intervals in sixteen young, healthy males forming two age matched groups. Significant variation was found in repeat ECGs at both periods. When precordial electrodes remained in situ between serial 10 minute recordings variation was reduced by approximately 60% We conclude that significant precordial voltage variation is present in serial electrocardiography, even when performed over the short term. Alteration in precordial electrode placement accounts for the major proportion of variation and this may be sufficiently large to interfere with the accurate interpretation of serial precordial voltage changes in an individual subject.