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[Chwastox D慢性毒性的形态学研究]

[Morphological studies of chronic toxicity of Chwastox D].

作者信息

Luciak M, Kita K, Kita I

出版信息

Med Pr. 1980;31(3):177-84.

PMID:7432157
Abstract

Chwastox D--herbicide for killing dicotyledonous weeds was evaluated toxicologically, basing on studies on the mass and morphological picture of internal organs of rats receiving, over 13 weeks, 15, 60, 240 and 960 mg/kg of feeding stuff containing this herbicide. The animals exposed for 13 weeks to different doses of Chwastox D were found to develop inspecific pathomorphotic changes, like disturbed circulation, retrogressive, progressive and inflammatory changes. The pathomorpohologic changes were found to be increased with 240 and 960 mg of stuff. The observations indicated that the maximum allowable dose for rats is 60 mg/kg of the feeding stuff.

摘要

Chwastox D(一种用于杀灭双子叶杂草的除草剂)基于对连续13周摄入含有该除草剂的饲料、剂量分别为15、60、240和960毫克/千克的大鼠内脏器官的质量和形态图的研究进行了毒理学评估。发现连续13周暴露于不同剂量Chwastox D的动物出现了非特异性病理形态学变化,如循环紊乱、退行性、进行性和炎症性变化。发现当饲料剂量为240和960毫克时,病理形态学变化有所增加。观察结果表明,大鼠的最大允许剂量为60毫克/千克饲料。

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