[Morphological studies of chronic toxicity of Chwastox D].

Chwastox D--herbicide for killing dicotyledonous weeds was evaluated toxicologically, basing on studies on the mass and morphological picture of internal organs of rats receiving, over 13 weeks, 15, 60, 240 and 960 mg/kg of feeding stuff containing this herbicide. The animals exposed for 13 weeks to different doses of Chwastox D were found to develop inspecific pathomorphotic changes, like disturbed circulation, retrogressive, progressive and inflammatory changes. The pathomorpohologic changes were found to be increased with 240 and 960 mg of stuff. The observations indicated that the maximum allowable dose for rats is 60 mg/kg of the feeding stuff.