Muntean W
Padiatr Padol. 1980;15(2):109-20.
The mechanisms involved in haemostasis develop early in gestational life. Vessel wall contractility, platelets and increasing activity of coagulation and fibrinolysis have been found as early as the tenth week of gestational age. The development is not completed at birth and lasts throughout the first year of life. Mainly impaired platelet function and lower activity of coagulation factors differ from findings in older children and adults. Despite these in vitro differences, mature newborn babies appear to have a well functioning haemostasis.
止血机制在孕期早期就已形成。早在孕龄第10周时就已发现血管壁收缩性、血小板以及凝血和纤溶活性的增强。这种发育在出生时并未完成，而是持续至生命的第一年。主要是血小板功能受损以及凝血因子活性较低，这与大龄儿童和成人的情况不同。尽管存在这些体外差异，但成熟的新生儿似乎具有良好的止血功能。
