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[环境及地塞米松对脑脊液吞噬细胞体外吞噬作用的影响(作者译)]

[Influence of milieu and dexamethasone on in vitro phagocytosis of cerebrospinal fluid phagocytes (author's transl)].

作者信息

Weitbrecht W U

出版信息

Pathol Res Pract. 1980;167(2-4):393-9. doi: 10.1016/s0344-0338(80)80068-9.

Abstract

The influence of milieu and dexamethazone on the phagocytosis of India ink by cerebrospinal fluid phagocytes was compared in the same sample of cerebrospinal fluid from different patients. The addition of phosphate buffer at pH 7.4 to cerebrospinal fluid increased phagocytosis significantly. Acid (pH 7.2) or alkaline (pH 7.6) milieu lowered phagocytosis significantly. Low doses of dexamethazone (200 ug/ml) did not influence phagocytosis; high doses (400 ug/ml) lowered phagocytosis significantly.

摘要

在来自不同患者的同一脑脊液样本中,比较了环境和地塞米松对脑脊液吞噬细胞吞噬印度墨汁的影响。向脑脊液中添加pH 7.4的磷酸盐缓冲液可显著增加吞噬作用。酸性(pH 7.2)或碱性(pH 7.6)环境会显著降低吞噬作用。低剂量地塞米松(200微克/毫升)不影响吞噬作用;高剂量(400微克/毫升)则会显著降低吞噬作用。

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