Lehman J A, Armitage J O
Postgrad Med. 1980 Nov;68(5):89-92, 95. doi: 10.1080/00325481.1980.11715591.
Aggressive chemotherapy has dramatically increased the number and duration of remissions in acute leukemia. Concomitant with improved survival has been an increased incidence of complications necessitating surgery in patients with chemotherapy-induced pancytopenia. In the past, patients such as the three described here rarely survived, whether managed conservatively or surgically. All three of these achieved partial or complete remisson. In view of our experience plus reports in the literature, we feel that aggressive surgical intervantion can result in a greater percentage of patients surviving the complications of therapy, and this in turn can lead to a higher incidence of complete remission.
积极的化疗显著增加了急性白血病缓解的次数和持续时间。在化疗导致全血细胞减少的患者中，伴随生存率提高而来的是需要手术治疗的并发症发生率增加。过去，像这里描述的三位患者这样的情况，无论采用保守治疗还是手术治疗，很少能存活下来。这三位患者均实现了部分或完全缓解。鉴于我们的经验以及文献报道，我们认为积极的手术干预可使更多患者在治疗并发症中存活下来，进而可导致更高的完全缓解率。
