Rees P J, Higenbottam T W, Clark T J
Thorax. 1980 May;35(5):384-8. doi: 10.1136/thx.35.5.384.
The use of a single pair of magnetometer coils placed centrally on the trunk to record tidal volumes and breath times has been evaluated in five normal subjects in five positions. Breath times were accurate in all positions tested but tidal volumes were only reliable with the subjects lying and the backrest raised to 45° or in the supine position only for volumes up to 1000 ml. Using this system, recordings have been made in seven patients with barbiturate overdose, five with salicylate overdose, and five undergoing anaesthesia with thiopentone. The single pair of coils was satisfactory for measuring changes in the pattern of breathing in these patients. In barbiturate overdose in five patients there was initially an increase in respiratory frequency with a decrease in tidal volume. As these patients recovered the tidal volume increased and the respiratory rate slowed. In two patients who had a raised PaCO there was initially reduction of both tidal volume and respiratory rate, both increasing as the patients recovered. Monitoring respiratory rate appears to be a useful guide in barbiturate overdose; a slowing of the rate without recovery of consciousness warrants further investigation to assess the need for ventilatory support. The single pair of coils were also satisfactory for measuring the increased tidal volume in salicylate overdose. As after other respiratory stimuli in man, increased ventilation occurred predominantly through changes in tidal volume and expiratory time while inspiratory time changed very little.
已在五名正常受试者的五个体位上,对将一对磁力计线圈置于躯干中央以记录潮气量和呼吸时间的方法进行了评估。在所有测试体位中,呼吸时间均准确,但只有当受试者躺卧且靠背抬高至45°时,或者仅在仰卧位且潮气量达1000毫升时,潮气量才可靠。使用该系统,已对7名巴比妥酸盐过量患者、5名水杨酸盐过量患者以及5名接受硫喷妥钠麻醉的患者进行了记录。这对线圈对于测量这些患者呼吸模式的变化是令人满意的。在5名巴比妥酸盐过量患者中,最初呼吸频率增加,潮气量减少。随着这些患者的恢复,潮气量增加,呼吸频率减慢。在两名动脉血二氧化碳分压升高的患者中,最初潮气量和呼吸频率均降低,随着患者恢复两者均增加。监测呼吸频率似乎是巴比妥酸盐过量时的一项有用指标;呼吸频率减慢而意识未恢复,值得进一步检查以评估是否需要通气支持。这对线圈对于测量水杨酸盐过量时增加的潮气量也令人满意。与人体受到其他呼吸刺激后一样,通气增加主要通过潮气量和呼气时间的变化实现,而吸气时间变化很小。