Agrawal S J, Srivastava A K
Toxicology. 1980;17(1):97-100. doi: 10.1016/0300-483x(80)90031-1.
Blood dyscrasia in a fish exposed to experimental manganese poisoning is described. Colisa fasciatus, a fresh water teleost, showed significant decreases in the total erythrocyte count, number of erythrocytes/1000 blood cells of all types, and in the hepatosomatic index (relative liver wt) after exposure for 90 h to 2500 mg/l manganese sulphate; the 96 h LC50 value was 2850 mg/l. The exposure also evoked leucocytosis due to an increase in the number of small lymphocytes. Other haematological characteristics, viz., total count of thrombocytes, distribution of immature red blood cells, thrombocytes and large lymphocytes/1000 blood cells, haematocrit, erythrocyte sedimentation rate, haemoglobin, and clotting time, did not differ significantly from the controls.
描述了一条暴露于实验性锰中毒的鱼的血液恶液质情况。条纹斗鱼，一种淡水硬骨鱼，在暴露于2500毫克/升硫酸锰90小时后，总红细胞计数、各类红细胞/1000个血细胞数量以及肝体指数（相对肝脏重量）显著下降；96小时半数致死浓度值为2850毫克/升。暴露还因小淋巴细胞数量增加引发白细胞增多。其他血液学特征，即血小板总数、未成熟红细胞分布、血小板和大淋巴细胞/1000个血细胞、血细胞比容、红细胞沉降率、血红蛋白和凝血时间，与对照组相比无显著差异。
