Stryker J A, Velkley D E
Strahlentherapie. 1980 Nov;156(11):754-8.
The effect of radiotherapy treatment unit and technique on body weight loss during 5 to 6 weeks of pelvic irradiation was assessed in 129 patients with cervix or endometrial cancer. The patients treated with the 60Co APPA technique lost 2.91 +/- 2.28 percent, whereas the patients treated with the 10-MV APPA technique lost only 1.30 +/- 2.58 percent (P = 0.003). The patients treated with the 60Co "box" technique lost 4.36 +/- 3.85 percent and the patients treated with the 10-MV "box" technique lost 2.00 +/- 2.69 percent (P = 0.04). Patients treated with 60Co experienced more nausea during treatment than the 10-MV patients but the incidence of diarrhea was similar for the treatment units. Weight loss during radiotherapy was somewhat greater for cervix patients and for patients having advanced disease but was not adversely affected by previous pelvic surgery. We conclude technical factors such as treatment unit and technique can influence the amount of weight lost by patients during pelvic irradiation.
对129例宫颈癌或子宫内膜癌患者评估了放疗治疗设备和技术对盆腔放疗5至6周期间体重减轻的影响。采用60钴APPA技术治疗的患者体重减轻了2.91±2.28%，而采用10兆伏APPA技术治疗的患者仅减轻了1.30±2.58%（P = 0.003）。采用60钴“盒式”技术治疗的患者体重减轻了4.36±3.85%，采用10兆伏“盒式”技术治疗的患者体重减轻了2.00±2.69%（P = 0.04）。与10兆伏治疗的患者相比，采用60钴治疗的患者在治疗期间恶心症状更严重，但两个治疗设备的腹泻发生率相似。宫颈癌患者和晚期疾病患者在放疗期间的体重减轻幅度稍大，但既往盆腔手术对其无不利影响。我们得出结论，诸如治疗设备和技术等技术因素可影响患者在盆腔放疗期间的体重减轻量。
