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移植到裸鼠体内的人卵黄囊瘤中甲胎蛋白的合成

Synthesis of alpha-fetoprotein by human yolk sac tumor transplanted into nude mice.

作者信息

Shirai T, Yoshiki T, Itoh T

出版信息

Gan. 1977 Dec;68(6):847-9.

PMID:74348
Abstract

All nude mice bearing primary or secondary transplants of a human yolk sac tumor exhibited a high serum alpha-fetoprotein level. This finding clearly indicates the synthesis of alpha-fetoprotein by the human yolk sac tumor and supports an idea that human yolk sac tumor simulates yolk sac endoderm not only morphologically but also functionally.

摘要

所有携带人卵黄囊瘤原发性或继发性移植瘤的裸鼠血清甲胎蛋白水平都很高。这一发现清楚地表明人卵黄囊瘤能合成甲胎蛋白,并支持了这样一种观点,即人卵黄囊瘤不仅在形态上而且在功能上都模拟卵黄囊内胚层。

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