Boewer C
Z Gesamte Inn Med. 1980 May 1;35(9):380-2.
The numerical behaviour of the leucocytes, thrombocytes and reticulocytes of 12 patients with megaloblastic anaemia before and after additional transfusion as well as after following parenteral therapy with vitamin B12 was investigated. Transfusions alone had no influence on the numbers of leukocytes thrombocytes and reticulocytes. After 4--5 days vitamin B12 led to a very inhibited crisis of reticulocytes in 9 of the 12 patients, in the others an increase did not take place. Thrombocytes and leukocytes appeared partly in form of a crisis in all patients after 6 to 9 days with normalisation of the values, latest after 14 days. The very reduced or lacking crisis of reticulocytes after treatment with vitamin B12 due to previous additional transfusion was discussed.
对12例巨幼细胞贫血患者在额外输血前后以及随后接受维生素B12肠外治疗后的白细胞、血小板和网织红细胞的数值变化进行了研究。单纯输血对白细胞、血小板和网织红细胞的数量没有影响。4至5天后，维生素B12导致12例患者中的9例出现网织红细胞非常受抑制的危机，其他患者则未出现增加。6至9天后，所有患者的血小板和白细胞部分出现危机，数值恢复正常，最晚在14天后。讨论了由于先前额外输血导致维生素B12治疗后网织红细胞危机非常减少或缺乏的情况。
