Harbert G M, Spisso K R
Am J Obstet Gynecol. 1980 Nov 15;138(6):686-96. doi: 10.1016/0002-9378(80)90089-7.
The association between the documented spontaneous biorhythms of uterine activity, uterine artery blood flow, and aortaic blood pressure and the processes of labor and delivery was explored in 17 nonmedcated rhesus monkeys for 18 pregnancies. The characteristic circadian variations of higher hourly average values of uterine activity during periods of light than during periods of darkness were incorporated in a statistically distinct, predictable, and repetitive manner into the events of parturition. Variations in uterine artery blood flow reflected changes in intra-amniotic pressure. In those animals in which delivery occurred at night, a shift in maximal values of uterine activity from periods of light to periods of darkness occurred 48 to 60 hours prior to delivery. Progressive linear increases in hourly average values of frequency of contraction and aortic blood pressure consistently began 24 to 36 hours prior to delivery. These changes suggest that specific, directly related prodromal events occur within the maternal organism hours before parturition in the nonhuman primate.
在17只未用药的恒河猴身上进行了18次妊娠研究，探讨了子宫活动、子宫动脉血流和主动脉血压的记录自发生物节律与分娩过程之间的关联。与黑暗时期相比，光照时期子宫活动每小时平均值较高的特征性昼夜变化以统计学上显著、可预测和重复的方式纳入分娩事件中。子宫动脉血流的变化反映了羊膜腔内压力的变化。在夜间分娩的动物中，子宫活动最大值从光照时期转移到黑暗时期发生在分娩前48至60小时。收缩频率和主动脉血压每小时平均值的逐步线性增加在分娩前24至36小时持续开始。这些变化表明，在非人类灵长类动物分娩前数小时，母体体内会发生特定的、直接相关的前驱事件。
