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Plasma cholinesterase changes during pregnancy. Their interpretation as a cause of suxamethonium-induced apnoea.

作者信息

Evans R T, Wroe J M

出版信息

Anaesthesia. 1980 Jul 7;35(7):651-4. doi: 10.1111/j.1365-2044.1980.tb03878.x.

DOI:10.1111/j.1365-2044.1980.tb03878.x
PMID:7435932
Abstract

Cholinesterase activities were measured on serum from 941 pregnant women distributed evenly throughout the 40 weeks of gestation. A rapid fall has been shown to occur during the first trimester to a level which did not alter significantly during the remainder of pregnancy. Even lower values were observed in 105 patients examined during the first 7 days following delivery. Enzyme activity was used to determine the probable incidence of a prolonged reaction to suxamethonium in obstetric patients. The risk was greatest in the immediate post partum period affecting 11% of the patients investigated.

摘要

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3
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