Vera Román J M, Bonet Arzo J
An Esp Pediatr. 1980 Aug;13(8):726-30.
In relation to a new case of scleredema "adultorum" (Buschke) observed by authors in a two year-old girl, they compare characteristics of this type of cutaneous induration with those of sclerodermia. Scleredema affects the neck region, face and upper thorax, and very rarely it reaches the hands, meanwhile in sclerodermia the hands and face, and some other possible cutaneous region and viscera are commonly affected. The former regresses in six months to two years, or rarely later; the second is progressive and permanent. Histologically, dermal collagen in increased in both but in the former the fibers are not condensed and hyalinized, as they are in the second.
