King J W, May J S
Arch Intern Med. 1980 Nov;140(11):1537-9.
We present a case of Legionnaires' disease complicated by cold agglutinin disease. Therapy with erythromycin gluceptate was associated with resolution of both the pneumonia and the hemolysis. Complement-fixing antibody levels to Mycoplasma pneumoniae, influenza A, and adenoviruses were measured repeatedly throughout the clinical illness and were persistently nondiagnostic. The cold agglutinin present in the patient's serum was characterized as an IgM that demonstrated anti-I specificity. Thus, Legionella pneumophila should be considered a potential causative agent in patients with pneumonia and cold agglutinin disease.
我们报告一例军团病合并冷凝集素病的病例。葡萄糖酸红霉素治疗使肺炎和溶血均得到缓解。在整个临床病程中反复检测了针对肺炎支原体、甲型流感病毒和腺病毒的补体结合抗体水平，结果一直无法确诊。患者血清中的冷凝集素被鉴定为具有抗I特异性的IgM。因此，嗜肺军团菌应被视为肺炎合并冷凝集素病患者的潜在病原体。
