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牙医中的肝炎、乙肝表面抗原和抗体

Hepatitis and hepatitis B surface antigen and antibody in dentists.

作者信息

Berris B, Feinman S V, Sinclair J C, Wrobel D

出版信息

Can Med Assoc J. 1978 Nov 4;119(9):1040-3.

Abstract

Dentists were surveyed regarding a history of hepatitis and the presence in the blood of hepatitis B surface antigen (HBsAg) and antibody (anti-HBs) to determine whether they were at high risk of exposure to hepatitis B virus. Of 288 Canadian dentists 5.2% gave a history of hepatitis after graduation. This proportion is similar to that for 1462 Ontario dentists (6.3%) and that for 3162 accountants (5.1%) who had previously completed a mailed questionnaire. One dentist (0.3%) was HBsAg-positive and 42 (14.6%) were anti-HBs-positive. Of 210 healthy volunteer blood donors matched for age, sex and ethnic origin with the group of dentists none was HBsAg-positive and 2.9% significantly fewer (P less than 0.005), were anti-HBs-positive. Among Ontario blood donors 0.3% were HBsAg-positive and 3% were anti-HBs-positive. Thus, in Canada, dentists are not at increased risk of acquiring clinical hepatitis or becoming carriers, but they are more likely than other groups to have anti-HBs in the blood. Among dentists from outside Canada a higher proportion had a history of hepatitis (10.3%) and were HBsAg-positive (1.6%), but approximately the same proportion were anti-HBs-positive (15.9%).

摘要

对牙医进行了关于肝炎病史以及血液中乙肝表面抗原(HBsAg)和抗体(抗-HBs)的检测,以确定他们是否处于感染乙肝病毒的高风险中。在288名加拿大牙医中,5.2%的人表示毕业后有肝炎病史。这一比例与之前完成邮寄问卷调查的1462名安大略省牙医(6.3%)以及3162名会计师(5.1%)的比例相似。有一名牙医(0.3%)HBsAg呈阳性,42名(14.6%)抗-HBs呈阳性。在210名年龄、性别和种族与牙医组相匹配的健康志愿者献血者中,没有人HBsAg呈阳性,抗-HBs呈阳性的比例显著减少2.9%(P小于0.005)。在安大略省的献血者中,0.3%的人HBsAg呈阳性,3%的人抗-HBs呈阳性。因此,在加拿大,牙医感染临床肝炎或成为携带者的风险并未增加,但他们血液中抗-HBs的可能性比其他群体更高。在来自加拿大境外的牙医中,有更高比例的人有肝炎病史(10.3%)且HBsAg呈阳性(1.6%),但抗-HBs呈阳性的比例大致相同(15.9%)。

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Letter: Frequency of hepatitis in dentists in Ontario.信件:安大略省牙医中肝炎的发病率
Ann Intern Med. 1974 Nov;81(5):699-700. doi: 10.7326/0003-4819-81-5-699.
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Hepatitis B antigen in saliva and mouth washings.唾液和漱口液中的乙型肝炎抗原。
Lancet. 1972 Oct 7;2(7780):726-7. doi: 10.1016/s0140-6736(72)92021-1.
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Hepatitis B virus infection in dentists.牙医中的乙型肝炎病毒感染
N Engl J Med. 1975 Oct 9;293(15):729-34. doi: 10.1056/NEJM197510092931501.

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