Gürtler R
Arch Geschwulstforsch. 1980;50(2):141-52.
This report is a review on the most frequent toxic side effects and complications arising from antineoplastic chemotherapy. Acute, delayed and late reactions are distinguished depending on the time interval between the begin of the treatment and the appearance of the first symptoms of the side effects. Priority is given to bone marrow depression and the valid guidelines for the treatment of the patients during the granulocytopenic period. Furthermore, the cardiomyopathies and the alteration of the lungs caused by the therapy with the cytostatic agents discussed as well as the available possibilities for therapy and prophylaxis are pointed out.
本报告是对肿瘤化疗中最常见的毒副作用及并发症的综述。根据治疗开始与副作用首次症状出现之间的时间间隔,区分急性、延迟性和晚期反应。重点关注骨髓抑制以及粒细胞缺乏期患者的有效治疗指南。此外,还讨论了细胞毒性药物治疗引起的心肌病和肺部改变,以及现有的治疗和预防方法。