大鼠耳蜗血管纹中维生素A的放射自显影定位

Autoradiographic localization of vitamin A in the stria vascularis of the rat cochlea.

作者信息

Chole R A

出版信息

Arch Otolaryngol. 1980 Dec;106(12):741-3. doi: 10.1001/archotol.1980.00790360019007.

DOI:10.1001/archotol.1980.00790360019007

Abstract

Vitamin A is present in the membranous cochlea at a higher concentration than in most other mammalian tissues. In order to localize this substance in the cochlea, 11(3)[H] retinyl acetate was administered to vitamin A-deficient rats. An autoradiographic study of these cochleas revealed labelling of the stria vascularis; the sensory cells and ganglion cells were not labelled.

摘要

维生素A在膜性耳蜗中的浓度高于大多数其他哺乳动物组织。为了在耳蜗中定位这种物质，将11(3)[H]醋酸视黄酯给予维生素A缺乏的大鼠。对这些耳蜗的放射自显影研究显示血管纹有标记；感觉细胞和神经节细胞未被标记。