Wilkins J F, Hamilton B A
Aust Vet J. 1980 Feb;56(2):87-9. doi: 10.1111/j.1751-0813.1980.tb05631.x.
The effectiveness of selenium pellets in grazing Merino sheep was examined by comparing the selenium status of treated and untreated animals over a 13 month period. The selenium status of treated sheep, as measured by blood glutathione peroxidase levels, had reached a maximum 3 months after treatment and there was a marked decline between 5 and 13 months. All pellets were recovered from treated sheep at slaughter this confirmed that the observed decline was not due to a loss of pellets. In a separate study sheep were slaughtered 14 months after treatment and some of the recovered pellets were readministered to sheep maintained on a low selenium diet. The selenium status of the sheep receiving recovered pellets remained low. This bioassay technique indicated that there was little available selenium released from these pellets. The selenium status of sheep given previously unused pellets was declining after 18 weeks.
通过比较13个月内经过处理和未经过处理的美利奴放牧绵羊的硒状态，研究了硒丸剂对其的有效性。用血液谷胱甘肽过氧化物酶水平衡量，经过处理的绵羊的硒状态在处理后3个月达到最高值，在5至13个月之间显著下降。在屠宰时从经过处理的绵羊体内回收了所有丸剂，这证实观察到的下降并非由于丸剂丢失。在另一项研究中，绵羊在处理后14个月被屠宰，一些回收的丸剂再次给予维持低硒饮食的绵羊。接受回收丸剂的绵羊的硒状态仍然很低。这种生物测定技术表明，这些丸剂释放的可利用硒很少。给予先前未使用过的丸剂的绵羊的硒状态在18周后下降。
