Jelinek P D, Steele P, Masters H G, Allen J G, Copland M D, Petterson D S
Aust Vet J. 1985 Oct;62(10):327-31. doi: 10.1111/j.1751-0813.1985.tb07651.x.
The relationship between in vitro erythrocyte 75Se uptake (75Se uptake) and erythrocyte glutathione peroxidase (EGSHPx) activity was examined in weaner sheep during periods of selenium depletion and repletion, to determine whether 75Se uptake was better correlated than EGSHPx activity to the development of weaner nutritional myopathy. In the 2 trials conducted, only 3 of 45 Merino wether weaners developed clinical myopathy and histological lesions in skeletal muscles. The 75Se uptake values and EGSHPx activities in these 3 sheep were no different from those in the unaffected sheep. There was a significant negative correlation between 75Se uptake values and EGSHPx activities over the entire period of the trials. It could not be demonstrated that 75Se uptake was any better correlated than EGSHPx activity to the development of nutritional myopathy, and it was concluded that EGSHPx activity indicated selenium status better than 75Se uptake in weaner sheep.
在断奶羔羊硒缺乏和补充硒的阶段，研究了体外红细胞对75硒的摄取（75硒摄取）与红细胞谷胱甘肽过氧化物酶（EGSHPx）活性之间的关系，以确定75硒摄取与EGSHPx活性相比，是否与断奶羔羊营养性肌病的发生有更好的相关性。在进行的2项试验中，45只美利奴断奶阉羊中只有3只出现了临床肌病和骨骼肌组织学损伤。这3只羊的75硒摄取值和EGSHPx活性与未受影响的羊没有差异。在整个试验期间，75硒摄取值与EGSHPx活性之间存在显著的负相关。无法证明75硒摄取与营养性肌病的发生比EGSHPx活性有更好的相关性，得出的结论是，在断奶羔羊中，EGSHPx活性比75硒摄取更能表明硒的状态。
