Cove J H, Holland K T, Cunliffe W J
Br J Dermatol. 1980 Oct;103(4):383-6. doi: 10.1111/j.1365-2133.1980.tb07260.x.
Bacteria were sampled using a "scrub" technique from the skin surface of the faces of forty-nine female subjects aged 18-21 years. The sebum excretion rate was determined by a gravimetric method and the level of free fatty acids by titration. The production rate of free fatty acids was calculated from the product of the concentration of free fatty acids in the sebum and the sebum excretion rate. The date was analysed using Kendall's rank correlation method. Positive correlations existed between the number of Micrococcaceae and the skin propionibacteria (P < 0.001) and between both groups of organisms and the production rate of free fatty acids (P < 0.001). There was no significant correlation between the size of the bacterial population and the sebum excretion rate. The results support the view that free fatty acids are produced as a result of bacterial action, that the Micrococcaceae and skin propionibacteria do not compete to the detriment of their respective populations, and that the size of the bacterial population is not dependent upon the sebum excretion rate.
采用“擦洗”技术，从49名年龄在18至21岁的女性受试者面部皮肤表面采集细菌样本。通过重量法测定皮脂分泌率，通过滴定法测定游离脂肪酸水平。游离脂肪酸的产生率由皮脂中游离脂肪酸浓度与皮脂分泌率的乘积计算得出。使用肯德尔等级相关法对数据进行分析。微球菌科的数量与皮肤丙酸杆菌之间存在正相关（P < 0.001），两组微生物与游离脂肪酸产生率之间也存在正相关（P < 0.001）。细菌种群大小与皮脂分泌率之间无显著相关性。这些结果支持以下观点：游离脂肪酸是细菌作用的结果，微球菌科和皮肤丙酸杆菌不会相互竞争而损害各自的种群数量，且细菌种群大小不依赖于皮脂分泌率。
