银屑病中芳烃羟化酶的全身性组织异常。
Generalised tissue abnormality of aryl hydrocarbon hydroxylase in psoriasis.
作者信息
Chapman P H, Kersey P J, Keys B, Shuster S, Rawlins M D
出版信息
Br Med J. 1980 Nov 15;281(6251):1315-6. doi: 10.1136/bmj.281.6251.1315.
Abstract
Microsomal aryl hydrocarbon hydroxylase (AHH) activity and inducibility were measured in jejunal mucosa, liver, and lesion-free epidermis of patients with psoriasis. In all three tissues AHH activity and inducibility were less than in controls. This demonstration of a generalised enzymatic abnormality in the tissues of patients with psoriasis is in keeping with the suggestion that it may be close to the underlying genetic defect.
摘要
对银屑病患者的空肠黏膜、肝脏和无病变表皮中的微粒体芳烃羟化酶（AHH）活性及诱导性进行了测定。在所有这三种组织中，AHH活性及诱导性均低于对照组。银屑病患者组织中这种普遍存在的酶异常现象表明，该病可能与潜在的基因缺陷密切相关。
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本文引用的文献
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