Knox B S, McKee J W, Hair P I, France J T
Clin Chem. 1980 Dec;26(13):1890-5.
We evaluated five quantitative, commercially available radioimmunoassay methods (Beta-Tec, BIO-RIA, Cambridge Nuclear, Mallinckrodt, and Serono) for rapid determination of the beta-subunit of human choriogonadotropin in serum or plasma. Only three of the kits (Beta-Tec, Mallinckrodt, and Serono) were found suitable for reliable determination of low concentrations of this analyte, which is of importance in the early diagnosis of trophoblastic disease in men and monitoring effectiveness of chemotherapy of trophoblastic tumors in men and women.
我们评估了五种定量的、市售的放射免疫分析方法（Beta-Tec、BIO-RIA、剑桥核科学公司、马林克罗德特公司和赛诺诺公司），用于快速测定血清或血浆中人绒毛膜促性腺激素的β亚基。结果发现，只有三种试剂盒（Beta-Tec、马林克罗德特公司和赛诺诺公司）适合可靠地测定该分析物的低浓度，这对于男性滋养细胞疾病的早期诊断以及监测男性和女性滋养细胞肿瘤化疗的有效性具有重要意义。
