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核心技术专利：CN118964589B侵权必究

核心技术专利：CN118964589B侵权必究

Dawson J, Bryant M G, Cox A G, Christofides N D, Bloom S R, Peters T J

Clin Sci (Lond). 1980 Dec;59(6):505-8. doi: 10.1042/cs0590505.

Analytical subcellular fractionation techniques have been applied to human jejunal homogenates to study the localization of serotonin and motilin. 2. Serotonin, detected by a fluorimetric assay, showed two distinct particulate distributions in the density gradients with modal densities of 1.14 and 1.20. Motilin, whether detected by N-terminal or C-terminal specific antibodies showed similar density distributions with a modal density of 1.20, coinciding with the denser peak of serotonin. 3. These results lend support to the histochemical suggestions that motilin is located in a a serotonin-containing granule.

已将分析性亚细胞分级分离技术应用于人类空肠匀浆，以研究血清素和胃动素的定位。2. 通过荧光测定法检测到的血清素在密度梯度中显示出两种不同的颗粒分布，其模态密度分别为1.14和1.20。胃动素，无论通过N端还是C端特异性抗体检测，都显示出相似的密度分布，模态密度为1.20，与血清素的较密峰一致。3. 这些结果支持了组织化学的观点，即胃动素位于含血清素的颗粒中。

Dawson J, Bryant M G, Cox A G, Christofides N D, Bloom S R, Peters T J

Clin Sci (Lond). 1980 Dec;59(6):505-8. doi: 10.1042/cs0590505.

Analytical subcellular fractionation techniques have been applied to human jejunal homogenates to study the localization of serotonin and motilin. 2. Serotonin, detected by a fluorimetric assay, showed two distinct particulate distributions in the density gradients with modal densities of 1.14 and 1.20. Motilin, whether detected by N-terminal or C-terminal specific antibodies showed similar density distributions with a modal density of 1.20, coinciding with the denser peak of serotonin. 3. These results lend support to the histochemical suggestions that motilin is located in a a serotonin-containing granule.

已将分析性亚细胞分级分离技术应用于人类空肠匀浆，以研究血清素和胃动素的定位。2. 通过荧光测定法检测到的血清素在密度梯度中显示出两种不同的颗粒分布，其模态密度分别为1.14和1.20。胃动素，无论通过N端还是C端特异性抗体检测，都显示出相似的密度分布，模态密度为1.20，与血清素的较密峰一致。3. 这些结果支持了组织化学的观点，即胃动素位于含血清素的颗粒中。