Le Lous M, Hors-Cayla M C, Hendrickx G F, Maroteaux P
Eur J Pediatr. 1980 Aug;134(2):159-60. doi: 10.1007/BF01846038.
Fibroblasts from a case of achondrogenesis type II and fibroblasts from a normal control donor were subcultivated in vitro in parallel. The lipid study on these cells showed similar total lipid content, free cholesterol level, phospholipid distribution and fatty acid patterns, while neutral glycerides were slightly more elevated in the control fibroblasts. The histological finding of Laxova et al. (1973) could not be confirmed.
对一名II型软骨发育不全患者的成纤维细胞和一名正常对照供体的成纤维细胞进行了体外平行传代培养。对这些细胞的脂质研究显示,总脂质含量、游离胆固醇水平、磷脂分布和脂肪酸模式相似,而对照成纤维细胞中的中性甘油酯略有升高。Laxova等人(1973年)的组织学发现未得到证实。