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蝎毒替尤斯毒素和哇巴因对大鼠脑孵育切片中乙酰胆碱释放的影响。

The effects of scorpion venom tityustoxin and ouabain on the release of acetylcholine from incubated slices of rat brain.

作者信息

Gomez M V

出版信息

Experientia. 1980 Aug 15;36(8):1007-8. doi: 10.1007/BF01953851.

Abstract

The in vitro release of acetylcholine in slices of rat brain tissue was followed in the presence of tityustoxin and ouabain. At low ouabain concentrations, the release of acetylcholine caused by both ouabain and tityustoxin, was additive. At higher ouabain concentrations the additive effect of tityustoxin and ouabain on the release of ACh was no longer observed.

摘要

在存在南美毒蛛毒素和哇巴因的情况下,对大鼠脑组织切片中乙酰胆碱的体外释放进行了跟踪研究。在低浓度哇巴因时,哇巴因和南美毒蛛毒素所引起的乙酰胆碱释放具有相加作用。在较高浓度哇巴因时,不再观察到南美毒蛛毒素和哇巴因对乙酰胆碱释放的相加作用。

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