An overview of seventeen years of experience with dothiepin in the treatment of depression in Europe.
作者信息
Goldstein B J, Claghorn J L
出版信息
J Clin Psychiatry. 1980 Dec;41(12 Pt 2):64-70.
PMID:7440528
Abstract
The European clinical experience with dothiepin since 1962 indicates that it is efficacious in the treatment of depression (neurotic, psychotic, and with concomitant anxiety) in dose of 75-200 mg/day. The side effects profile is similar to the tricyclic antidepressant drugs with significantly less anticholinergic side effects and cardiotoxicity then amitriptyline. The result of the current ongoing clinical trails in the United States with several hundred patients will more precisely define the efficacy, dosage and side effect profile of dothiepin.
摘要
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引用本文的文献
1
The drug treatment of depression in general practice: a comparison of nocte administration of trazodone with mianserin, dothiepin and amitriptyline.全科医疗中抑郁症的药物治疗：曲唑酮夜间给药与米安色林、多塞平及阿米替林的比较
Psychopharmacology (Berl). 1988;95 Suppl:S18-24. doi: 10.1007/BF00172625.
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