Glass A R, Mellitt R, Burman K D, Wartofsky L, Swerdloff R S
Endocrinology. 1978 Jun;102(6):1925-8. doi: 10.1210/endo-102-6-1925.
Serum triiodothyronine (T3) in rats did not change if food intake was restricted without altering the composition of the diet. Feeding a hypocaloric low-protein high-carbohydrate diet caused increases in serum T3, while feeding a hypocaloric high-protein low-carbohydrate diet caused decreases in serum T3. These changes were not related to reductions in intake of either calories or protein, and concomitant changes in serum thyroxine (T4) were not observed. Reduction in the dietary content of valine, without changes in the percentage of carbohydrate in the diet, caused increases in serum T3 when compared to growth-matched controls on a diet with normal valine concentration. Serum T3 in undernourished rats depends on the composition of the diet and not on total intake of calories or protein.
如果限制大鼠的食物摄入量而不改变饮食组成，其血清三碘甲状腺原氨酸（T3）不会发生变化。喂食低热量、低蛋白、高碳水化合物饮食会导致血清T3升高，而喂食低热量、高蛋白、低碳水化合物饮食则会导致血清T3降低。这些变化与热量或蛋白质摄入量的减少无关，且未观察到血清甲状腺素（T4）的相应变化。与缬氨酸浓度正常的生长匹配对照组相比，在饮食中碳水化合物百分比不变的情况下，减少缬氨酸的饮食含量会导致血清T3升高。营养不良大鼠的血清T3取决于饮食组成，而非热量或蛋白质的总摄入量。
