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埃博拉出血热:1977 - 1978年,扎伊尔坦达拉

Ebola hemorrhagic fever: Tandala, Zaire, 1977-1978.

作者信息

Heymann D L, Weisfeld J S, Webb P A, Johnson K M, Cairns T, Berquist H

出版信息

J Infect Dis. 1980 Sep;142(3):372-6. doi: 10.1093/infdis/142.3.372.

DOI:10.1093/infdis/142.3.372
PMID:7441008
Abstract

Ebola virus was recovered from a nine-year-old girl who died of acute hemorrhagic fever in June 1977 at Tandala Hospital in northwestern Zaire, in the first reported recognized case of this disease since the discovery epidemics of 1976 in Zaire and Sudan. Investigations undertaken in the Tandala region revealed that two previous clinical infections with Ebola virus had occurred in 1972 and that about 7% of the residents had immunofluorescent antibodies to the virus. Females younger than 30 years of age had a higher prevalence of antibodies than males of comparable age, but above the age of 30 years there was no sex difference. No other clues to the still-mysterious natural reservoir of Ebola virus were uncovered.

摘要

1977年6月,在扎伊尔西北部的坦达拉医院,从一名死于急性出血热的9岁女孩身上分离出了埃博拉病毒,这是自1976年扎伊尔和苏丹发现疫情以来首次报告的该疾病确诊病例。在坦达拉地区进行的调查显示,1972年曾发生过两例先前的埃博拉病毒临床感染病例,约7%的居民对该病毒有免疫荧光抗体。30岁以下的女性抗体患病率高于同龄男性,但30岁以上则无性别差异。没有发现关于埃博拉病毒仍然神秘的天然宿主的其他线索。

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