Hinghofer-Szalkay H, Wurm H
J Clin Chem Clin Biochem. 1980 Oct;18(10):615-9.
Sampling of capillary blood often yields slightly hemolytic plasma. We investigated the influence of hemolysis on plasma density using the mechanical oscillator technique. Plasma density rose by approximately 0.1 milligram when the hemoglobin content increased by 0.5 milligram. These values correspond to 0.3% hemolysis and were not exceeded in more than 70% of the investigated capillary plasma samples. In general, hemolysis must be taken into account if plasma density measurements are to be made with an accuracy better than 0.5 milligram, which corresponds to 2-3% of the plasma protein content.
采集毛细血管血通常会得到轻度溶血的血浆。我们使用机械振荡技术研究了溶血对血浆密度的影响。当血红蛋白含量增加0.5毫克时,血浆密度大约升高0.1毫克。这些数值相当于0.3%的溶血率,并且在所研究的70%以上的毛细血管血浆样本中未超过此值。一般来说,如果要进行精度优于0.5毫克(相当于血浆蛋白含量的2 - 3%)的血浆密度测量,就必须考虑溶血的影响。