Barnard R O, Pambakian H
J Neurol Neurosurg Psychiatry. 1980 Nov;43(11):1041-4. doi: 10.1136/jnnp.43.11.1041.
A case of cerebellar medulloblastoma with transitional features towards malignant fibrillary astrocytoma is described. In the cerebellum the tumour is characterised by extensive subpial infiltration with cells of undifferentiated type, and the astrocytic component could only be identified by a positive glial fibrillary acidic protein reaction. In the brainstem the character of the growth transforms to that of diffuse astrocytoma. This demonstrates the potential for differentiation existing in a "primitive" neuroepithelial neoplasm.
描述了一例具有向恶性纤维性星形细胞瘤过渡特征的小脑髓母细胞瘤。在小脑中，肿瘤的特征是未分化型细胞广泛的软膜下浸润，星形细胞成分只能通过胶质纤维酸性蛋白反应阳性来识别。在脑干中，生长特征转变为弥漫性星形细胞瘤。这证明了一种“原始”神经上皮肿瘤中存在的分化潜力。
