Chaput M, Holley A
J Physiol (Paris). 1980 Nov;76(6):551-8.
The changes in single unit activity induced by short odour presentations were studied in the olfactory bulbs of awake rabbits. 1. It was found that an accurate evaluation of the cell responses required the separate processing of the inspiration- and expiration-related activity. 2. Three main types of response were observed during odour presentation. One was characterized by an increase in firing over several successive inspirations, with a decrease in the corresponding expiratory phases. The other two were characterized by an inspiration-related increase or decrease in activity without any modifications during expiration. 3. The end of odour presentation led to inconsistent "off-effects" in the cells affected by the stimulation. The most conspicuous were: a complete cessation of the firing for several respiratory cycles following an excitation, an excitatory rebound following inhibition, a reversal of the respiratory phase-related discharge, i.e., activity decrease during inspiration and the increase during expiration. 4. The findings are discussed with reference to previous studies on anaesthetized animals, together with their relevance to sensory coding in the olfactory bulb.
在清醒兔子的嗅球中研究了由短暂气味呈现引起的单个神经元活动的变化。1. 发现对细胞反应进行准确评估需要分别处理与吸气和呼气相关的活动。2. 在气味呈现期间观察到三种主要的反应类型。一种表现为在连续几次吸气过程中放电增加，而在相应的呼气阶段放电减少。另外两种表现为与吸气相关的活动增加或减少，呼气期间没有任何变化。3. 气味呈现结束导致受刺激细胞出现不一致的“关闭效应”。最明显的是：兴奋后几个呼吸周期完全停止放电，抑制后出现兴奋性反弹，呼吸相位相关放电反转，即吸气期间活动减少而呼气期间活动增加。4. 结合之前对麻醉动物的研究讨论了这些发现，以及它们与嗅球中感觉编码的相关性。
