Anshelevich Iu V, Sorokin T A
Kardiologiia. 1980 Oct;20(10):54-7.
Single intravenous injection of drugs arrests 1/3 of atrial fibrillation paroxysms and only 1/7 of atrial flutter paroxysms. According to the frequency of the arresting effect in paroxysms of atrial fibrillation, isoptin, a combination of procaine hydrochloride with strophanthin, and giluritmal take first place. In paroxysms of atrial flutter, isoptin produces the best effect. Combined antiarrhythmic therapy with several drugs results in the arrest of about 50% of tachyarrhythmia paroxysms in a few hours to 10 days. Emergency indications for the application of electric-pulse therapy are noted among 7.9% of patients with fibrillation and among 6.6% of those with flutter of the atria.
单次静脉注射药物可使三分之一的房颤发作和仅七分之一的房扑发作停止。根据对阵发性房颤发作的抑制效果频率,盐酸普鲁卡因与毒毛旋花子苷的组合药物异搏定以及乙胺碘呋酮位居首位。在房扑发作中,异搏定产生的效果最佳。几种药物联合抗心律失常治疗可在数小时至10天内使约50%的快速心律失常发作停止。在7.9%的房颤患者和6.6%的房扑患者中发现了应用电脉冲治疗的紧急指征。