Schwartz R A, Burgess G H, Holtermann O A, Baitman L, Milgrom H, Klein E, Case R W, Kenny P G, Birnkrant A P, Yaqub M
J Surg Oncol. 1980;14(4):347-57. doi: 10.1002/jso.2930140409.
We report a 59-year-old woman with disease manifestations diagnosed as mycosis fungoides (MF), as well as findings of sarcoidosis. The concurrence of these two disorders, both of which may be associated with basic immunopathogenic factors, has been reported. Histologically, the cutaneous findings of both non-caseating granulomas and an infiltrate compatible with MF in the same site leads to a discussion of granulomatous MF. Whether granulomatous MF simply represents sarcoidosis developing concomitantly with MF lymphoma or is, in fact, a distinct clinical and histologic type of MF is discussed. Reasons why granulomatous MF, like granulomators Hodgkin disease, might have a more favorable prognosis than the usual type of MF are considered.
我们报告了一名59岁女性，其疾病表现被诊断为蕈样肉芽肿（MF），同时还有结节病的表现。这两种疾病都可能与基本的免疫致病因素相关，此前已有二者并发的报道。组织学上，同一部位出现非干酪样肉芽肿和符合MF的浸润的皮肤表现引发了对肉芽肿性MF的讨论。讨论了肉芽肿性MF是仅仅代表与MF淋巴瘤同时发生的结节病，还是实际上是一种独特的临床和组织学类型的MF。还考虑了为什么肉芽肿性MF，就像肉芽肿性霍奇金病一样，可能比普通类型的MF预后更好的原因。
