一种评估药物对大鼠胃排空影响的简化方法。
A simplified method for assessing drug effects on gastric emptying in rats.
作者信息
Droppleman D A, Gregory R L, Alphin R S
出版信息
J Pharmacol Methods. 1980 Nov;4(3):227-30. doi: 10.1016/0160-5402(80)90014-5.
PMID:7442267
Abstract
A method is described to determine the effects of experimental compounds on gastric emptying in rats. The technique, using a methylcellulose-based test meal, is simple, versatile and reliable. Data are presented to show the utility of the method in demonstrating both enhancement and inhibition of gastric emptying.
摘要
本文描述了一种测定实验化合物对大鼠胃排空影响的方法。该技术使用基于甲基纤维素的测试餐，简单、通用且可靠。文中给出的数据表明了该方法在证明胃排空增强和抑制方面的实用性。
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