睾酮对大鼠前列腺中雌二醇定位的影响。
Effects of testosterone on estracyt localization in rat prostate.
作者信息
Catane R, Mittelman A, Murphy G P, Sandberg A A
出版信息
Oncology. 1980;37(5):357-9. doi: 10.1159/000225469.
PMID:7443167
Abstract
Testosterone administration to castrated rats leads to increased concentrations of radioactivity associated with estracyt (a conjugate of carbamate with E2) in the prostate gland, particularly the ventral prostate. This contracts with the decreased concentrations of labeled E2. The findings appear to shed further light on the possible mechanism of action of estracyt in cancer of the prostate.
摘要
给去势大鼠注射睾酮会导致前列腺，尤其是腹侧前列腺中与雌二醇氮芥（一种氨基甲酸酯与雌二醇的结合物）相关的放射性浓度增加。这与标记的雌二醇浓度降低形成对比。这些发现似乎进一步揭示了雌二醇氮芥在前列腺癌中可能的作用机制。
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