Kramer M, von Korff M, Kessler L
Psychol Med. 1980 Aug;10(3):429-35. doi: 10.1017/s0033291700047310.
The age-specific lifetime prevalence rate of a disease is the proportion of persons surviving to a given age who have experienced the disease at any time during their lives. This measure of morbidity has been used to report findings in many of the epidemiological surveys of mental disorders of the last 30 years. This paper presents a life-table method for estimating age-specific lifetime prevalence rates from incidence and mortality data. The method is applied to Monroe County, New York, case register data on the incidence of schizophrenia. Using this method, we estimate that at least 3% of the White population surviving to age 55 have experienced an episode of schizophrenia at some time during their lives. The difficulties of producing valid estimates of lifetime prevalence and the difficulties in interpreting differences reported in such rates make this morbidity measure of secondary importance to incidence and point-prevalence data.
某疾病的年龄别终生患病率是活到某一特定年龄的人群中，在其一生中任何时间患过该疾病的人群比例。在过去30年的许多精神障碍流行病学调查中，这种发病率测量方法被用于报告研究结果。本文提出了一种根据发病率和死亡率数据估计年龄别终生患病率的生命表方法。该方法应用于纽约门罗县精神分裂症发病率的病例登记数据。使用这种方法，我们估计活到55岁的白人人口中，至少有3%在其一生中的某个时候经历过精神分裂症发作。得出终生患病率有效估计值的困难，以及解释此类患病率报告差异的困难，使得这种发病率测量相对于发病率和时点患病率数据而言，重要性次之。
