Hansen M S, Clemmensen I, Winther D
Scand J Clin Lab Invest. 1980 May;40(3):221-6. doi: 10.3109/00365518009095570.
A qualitatively abnormal fibrinogen was detected in the plasma of a 53 year old woman with severe arterial thrombotic disease. The concentrations of plasma fibrinogen and serum fibrinogen related material were normal. The abnormal fibrinogen was electrophoretically normal. The defects detected were an abnormality of polymerization of fibrin monomers and a decreased rate of release of fibrinopeptide A. The absorption of radiolabelled partially degraded plasminogen on to fibrin prepared from purified fibrinogen Copenhagen was normal.
在一名患有严重动脉血栓性疾病的53岁女性的血浆中检测到一种定性异常的纤维蛋白原。血浆纤维蛋白原和血清纤维蛋白原相关物质的浓度正常。该异常纤维蛋白原在电泳上是正常的。检测到的缺陷是纤维蛋白单体聚合异常和纤维蛋白肽A释放速率降低。放射性标记的部分降解的纤溶酶原在由纯化的哥本哈根纤维蛋白原制备的纤维蛋白上的吸附是正常的。
