Bowden C L, Fisher J G
South Med J. 1980 Dec;73(12):1581-4. doi: 10.1097/00007611-198012000-00014.
Clinical evidence of withdrawal phenomena and efficacy was studied in 23 long-term users of diazepam (15 to 50 mg daily). No withdrawal reactions were observed in the ten patients who received placebo in a double-blind fashion for a two-week period. Changes in anxiety scores of both patients who received placebo and those who received diazepam suggest that the diazepam continued to be effective when used for one year or longer.
对23名长期使用地西泮（每日15至50毫克）的患者进行了戒断现象和疗效的临床证据研究。在为期两周的双盲试验中，接受安慰剂的10名患者未观察到戒断反应。接受安慰剂和接受地西泮的患者焦虑评分的变化表明，地西泮使用一年或更长时间时仍持续有效。
