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奥克太尔-双羟萘酸噻嘧啶用于治疗土源性蠕虫感染。

Oxantel-pyrantel pamoate for the treatment of soil-transmitted helminths.

作者信息

Margono S S, Mahfudin H, Rasidi R, Rasad R

出版信息

Southeast Asian J Trop Med Public Health. 1980 Sep;11(3):384-6.

PMID:7444580
Abstract

A mixture of oxantel-pyrantel pamoate was given to 147 primary school children. A single daily dose of 15 mg per kg body weight was administered to cases with Ascaris lumbricoides and Trichuris trichiura infections. The same single daily dose was given for three consecutive days to 10 cases with hookworm infections. The cure rate was 93.7% for ascariasis and the egg reduction rate was 98.2%. A cure rate and an egg reduction rate for trichuriasis was 70.2% and 86.5% respectively. All cases with hookworm infection were cured. Side effects were light and did not cause any anxiety.

摘要

给147名小学生服用了奥克太尔-双羟萘酸噻嘧啶合剂。对感染蛔虫和鞭虫的病例,按每公斤体重每日15毫克的剂量单次给药。对10例钩虫感染病例连续三天给予相同的每日单次剂量。蛔虫病的治愈率为93.7%,虫卵减少率为98.2%。鞭虫病的治愈率和虫卵减少率分别为70.2%和86.5%。所有钩虫感染病例均治愈。副作用轻微,未引起任何担忧。

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