Fiumara N J, Schmidt-Ulrick B, Comite H
Sex Transm Dis. 1980 Jul-Sep;7(3):130-2. doi: 10.1097/00007435-198007000-00008.
This report describes the cases of seven patients who had primary genital infection with herpes simplex virus and whose initial nontreponemal and treponemal tests for syphilis were nonreactive. On routine posttreatment examination, a change in the consistency of the ulcers was noticed, and the inguinal nodes, which had been soft and tender, were hard and non-tender. The morphologic changes indicated the probable presence of concomitant primary infection with Treponema pallidium, which was confirmed serologically for all seven patients and by a positive darkfield examination for two patients. Clinicians should be aware that different sexually transmitted diseases often coexist. Patients who have primary genital herpes should be followed clinically and serologically until recovery is complete.
本报告描述了7例原发性单纯疱疹病毒生殖器感染患者的病例，这些患者最初的梅毒非梅毒螺旋体和梅毒螺旋体检测均为阴性。在常规治疗后检查中，发现溃疡的质地发生了变化，腹股沟淋巴结原本柔软且有压痛，现在变硬且无压痛。形态学变化表明可能同时存在梅毒螺旋体原发性感染，这在所有7例患者中均通过血清学得到证实，2例患者通过暗视野检查呈阳性得到证实。临床医生应意识到不同的性传播疾病常并存。原发性生殖器疱疹患者应进行临床和血清学随访，直至完全康复。
