Sischy A, da L'Exposto F, Dangor Y, Fehler H G, Radebe F, Walkden D D, Miller S D, Ballard R C
Department of Microbiology, School of Pathology, University of the Witwatersrand, Johannesburg, South Africa.
Genitourin Med. 1991 Apr;67(2):129-32. doi: 10.1136/sti.67.2.129.
The reactivity of a non-specific reagin (RPR) test and a specific treponemal (FTA-ABS) test were determined in 21 patients with primary syphilis, 430 patients with proven non-treponemal genital ulcerations and 719 patients with acute urethritis presenting at a clinic for sexually transmitted diseases in southern Africa. Excluding those 21 cases of primary syphilis, 358 of 1149 tests performed (31%) were found to be reactive by at least one test. The rate of false positive RPR tests was very low (0.02%). Significantly higher rates of seropositivity were detected in patients with genital ulcerations than in patients with acute urethritis. The highest rates were detected among patients with proven lymphogranuloma venereum (34% RPR positive, FTA-ABS positive; 19% RPR negative, FTA-ABS positive). The geometric mean titres (GMT) of positive RPR tests in non-treponemal infections were found to be lower than in darkfield positive cases of genital ulcer disease.
在非洲南部一家性传播疾病诊所，对21例一期梅毒患者、430例确诊为非梅毒螺旋体性生殖器溃疡患者以及719例急性尿道炎患者进行了非特异性反应素（RPR）试验和特异性梅毒螺旋体（FTA-ABS）试验。排除21例一期梅毒病例后，在1149次检测中，有358次（31%）至少一项检测呈阳性。RPR试验假阳性率极低（0.02%）。生殖器溃疡患者的血清阳性率显著高于急性尿道炎患者。在确诊为性病性淋巴肉芽肿的患者中检测到的阳性率最高（RPR阳性、FTA-ABS阳性为34%；RPR阴性、FTA-ABS阳性为19%）。发现非梅毒螺旋体感染中RPR试验阳性的几何平均滴度（GMT）低于生殖器溃疡疾病暗视野阳性病例。
