[低剂量电离辐射作用下采用适度缺氧保护小鼠和猴骨髓的细胞遗传学效应]
[Cytogenetic effect of protecting the bone marrow of mice and monkeys by using measured hypoxia in the action of low ionizing radiation doses].
作者信息
Kosichenko L P, Chizhov A Ia, Rogozkin V D, Ronin M Ia, Preobrazhenskiĭ Iu Iu
出版信息
Tsitol Genet. 1980 Mar-Apr;14(2):27-31.
PMID:7445075
Abstract
The statistical reliable cytogenetic effect on bone marrow cells of mice and monkeys was achieved by means of dosage hypoxic hypoxia produced by breathing of gas hypoxic mixture containing 10% oxygen and 90% nitrogen (GHM-10). The effect was detested after total irradiation of mice and local irradiation of monkeys. The dose of irradiation was 100 rad (10 R/min and 17.4 R/min).
摘要
通过让小鼠和猴子呼吸含10%氧气和90%氮气的低氧混合气体（GHM - 10）产生的剂量性低氧低氧症，在小鼠和猴子的骨髓细胞上实现了统计学上可靠的细胞遗传学效应。在对小鼠进行全身照射和对猴子进行局部照射后检测到了该效应。照射剂量为100拉德（10拉德/分钟和17.4拉德/分钟）。
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