Kececioglu D, Hort W
Z Kardiol. 1980 Jun;69(6):398-405.
137 hears with 185 infarctions with a diameter of at least 2.5 cm were investigated. Sometimes the infarcted areas were supplied by two arteries. Altogether there were 198 arteries supplying infarcted areas (= IA) and 213 arteries supplying non-infarcted areas (= NIA). The cross-sectional area of most severe stenosis of each coronary artery was determined and expressed in per cent of the area surrounded by the lamina elastica interna. Only two groups of infarctions were formed: recent infarcts (without and with organization) and old infarcts (completely scarred). Regarding all IA and NIA there were highly significant differences between the mean values. The rest of the lumen amounted in the IA 7.48% and in the NIA 38.20%. In hearts with recent infarcts, IA were significantly smaller (4.13%) than in hearts with old infarcts 8.75%). This difference is due to recanalizations in the group of old infarcts. Differences between the degree of stenosis of sole and repeated infarcts were missed and there was no correlation between the weight of the heart and the cross-sectional area of IAs. The IA of hearts with transmural infarction were constricted more strongly than those of hearts with subendocardial infarcts. 21 IA were larger than one NIA of the same heart. Most of these hearts included old infarcts and it is most probably that during the origin of the infarctions almost all of these IA were smaller than the NIA. The findings strongly support the coronarogenic origin of myocardial infarctions.
对137例心脏中有185处直径至少为2.5厘米的梗死灶进行了研究。梗死区域有时由两条动脉供血。总共有198条动脉供应梗死区域(=IA),213条动脉供应非梗死区域(=NIA)。测定了每条冠状动脉最严重狭窄处的横截面积,并以弹力内膜所包围面积的百分比表示。梗死灶仅形成两组:近期梗死灶(无机化和有机化)和陈旧梗死灶(完全瘢痕化)。就所有的IA和NIA而言,平均值之间存在高度显著差异。IA的剩余管腔为7.48%,NIA为38.20%。在有近期梗死灶的心脏中,IA显著小于有陈旧梗死灶的心脏(分别为4.13%和8.75%)。这种差异是由于陈旧梗死灶组中的再通现象。未发现单一梗死灶和反复梗死灶狭窄程度之间的差异,且心脏重量与IA的横截面积之间无相关性。透壁性梗死心脏的IA比心内膜下梗死心脏的IA收缩更强烈。21处IA大于同一心脏的一处NIA。这些心脏大多包括陈旧梗死灶,很可能在梗死灶形成过程中,几乎所有这些IA都小于NIA。这些发现有力地支持了心肌梗死的冠状动脉起源。