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[膀胱癌与老年。德意志民主共和国关于老年膀胱癌的发病情况及诊断现状研究]

[Bladder cancer and old age. Study of the occurrence and status of diagnosis in the GDR with respect to old age].

作者信息

Berndt H, Berndt R, Brunz K H, Gemperle A, Gemperle I, Hansche G, Hansche R, Hünerbein C, Weber H G, Weber S, Witt K

出版信息

Z Urol Nephrol. 1980 Feb;73(2):123-36.

PMID:7445779
Abstract

Bladder cancer and age. A study on the morbidity and on the state of detection and treatment with respect to age in the G.D.R. Malignant neoplasms of the urinary bladder account for about 1,400 registered new cancer cases and 1,100 deaths annually in the G.D.R. As compared with other developed industrialized countries, incidence and mortality from bladder cancer is relatively low in the G.D.R. Analysis of age-standardized incidence and mortality from 1956 to 1974 gives no clearcut evidence of an increase of bladder cancer morbidity. A regional analysis of the state of detection and treatment of bladder cancer was performed in the capital Berlin (1955-1974) and the city of Dresden (1969/70). It can be shown that there is a decrease of localized stages, of radically operated tumours and of survival rates with increasing age at time of diagnosis. In Berlin more than 30 per cent of new cases are 75 years and older. Localized stages I and II amount to nearly 50 per cent of newly registered bladder cancer cases. While mean age of patients increased in the observation period and stage distribution remained about equal, rate of radical interventions showed a slight increase reflecting a more aggressive approach to treatment. Higher survival rates can be expected in the future.

摘要

膀胱癌与年龄。德意志民主共和国关于膀胱癌发病率以及不同年龄组的诊断和治疗状况的一项研究。在德意志民主共和国,每年约有1400例新登记的膀胱癌病例和1100例死亡。与其他发达工业化国家相比,德意志民主共和国的膀胱癌发病率和死亡率相对较低。对1956年至1974年年龄标准化发病率和死亡率的分析没有明确证据表明膀胱癌发病率有所增加。对首都柏林(1955 - 1974年)和德累斯顿市(1969/70年)的膀胱癌诊断和治疗状况进行了区域分析。结果显示,随着诊断时年龄的增加,局限性肿瘤分期、根治性手术切除的肿瘤以及生存率均有所下降。在柏林,超过30%的新病例年龄在75岁及以上。局限性I期和II期病例占新登记膀胱癌病例的近50%。在观察期内,患者的平均年龄增加,分期分布保持大致相同,而根治性干预率略有上升,这反映出治疗手段更为积极。未来有望实现更高的生存率。

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