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[德意志民主共和国首都柏林的胃癌——诊断与治疗状况分析]

[Malignant neoplasms of the stomach in Berlin, capital of the G.D.R. - An analysis of the state of diagnosis and treatment].

作者信息

Berndt H, Dietrich D, Gregor M, Hansche G, Hansche R, Witt K

出版信息

Arch Geschwulstforsch. 1976;46(1):15-23.

PMID:962498
Abstract

In Berlin, capital of the German Democratic Republic, 7,386 new cases of gastric cancer (ICD 151) were registered in the period from 1955 to 1969 and in year 1973. 52 percent of patients were male. Percentage of cases 75 years old and more, increased from 21% (1955-1959) to 36% (1965-1969). There were only slight changes in incidence. About 30% of cases were in the operable stages I and II. With rising age, the proportion of the advanced stages III and IV increases. No real progress as made in early diagnosis of stomach cancer as measured by stage distribution during observation period. Patient's delay from first symptom to first visit was shorter than one month in 40%, physician's delay from first visit to correct diagnosis was shorter than one month in 54%. 15% of patients were treated within one month after first symptom and 47% within three months. There was no correlation between duration of history and percentage of early stages. When observation periods 1955 to 1959, 1960-1964, 1965-1969 and 1973 are compared, we find an increase in old patients (75+ years), a decrease of localized stages I + II, and a decrease in resection rate. Therefore, a decrease in survival rates is to be expected. Crude 5-year survival rate was 6.4% (1955-1959) and 6.2% (1960-1964). When we compare data from Berlin with observations in the Region of Erfurt and in Birmingham Region, the situation of detection and treatment of stomach cancer in Berlin seems to be somewhat better. Finally, some suggestions for the improvement of control of stomach cancer are made.

摘要

在德意志民主共和国的首都柏林,1955年至1969年以及1973年期间,共登记了7386例胃癌新病例(国际疾病分类代码151)。患者中52%为男性。75岁及以上患者的病例百分比从21%(1955 - 1959年)增至36%(1965 - 1969年)。发病率仅有轻微变化。约30%的病例处于可手术的I期和II期。随着年龄增长,III期和IV期晚期病例的比例增加。在观察期内,以分期分布衡量,胃癌的早期诊断并未取得实质性进展。40%的患者从首次出现症状到首次就诊的延迟时间短于1个月,54%的患者从首次就诊到正确诊断的医生延迟时间短于1个月。15%的患者在首次出现症状后1个月内接受治疗,47%在3个月内接受治疗。病史时长与早期病例百分比之间无相关性。比较1955年至1959年、1960 - 1964年、1965 - 1969年和1973年的观察期,我们发现老年患者(75岁及以上)增加,I + II期局部病变减少,切除率降低。因此,预计生存率会下降。粗略的5年生存率在1955 - 1959年为6.4%,在1960 - 1964年为6.2%。当我们将柏林的数据与爱尔福特地区和伯明翰地区的观察结果进行比较时,柏林胃癌的检测和治疗情况似乎略好一些。最后,针对改善胃癌控制提出了一些建议。

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