Shamardin V A, Karal'nik B V
Zh Mikrobiol Epidemiol Immunobiol. 1980 Sep(9):49-52.
A new method for the nonspecific sensitization of erythrocytes with IgG by means of aqueous rivanol solution has been developed. Erythrocytic diagnostic reagents are intended for detecting reagents active against the Fc fragment of IgG (staphylococcal protein A, rheumatoid factor, Clq, etc.). This method is more sensitive than Boyden's sensitization methods with the use of chronic chloride, alizarin blue indicator. The active areas of the Fab fragment of IgG are blocked on the erythrocytic surface, which constitutes an important feature of sensitization by means of rivanol.
已开发出一种通过利凡诺水溶液对红细胞进行非特异性IgG致敏的新方法。红细胞诊断试剂旨在检测对IgG的Fc片段有活性的试剂（葡萄球菌蛋白A、类风湿因子、Clq等）。该方法比使用氯化铬、茜素蓝指示剂的博伊登致敏方法更灵敏。IgG的Fab片段的活性区域在红细胞表面被封闭，这是利凡诺致敏的一个重要特征。
