Domański T, Trojanowska B
Acta Physiol Pol. 1980 Jul-Aug;31(4):439-47.
In this work, results of investigations of the rate of lead incorporation into compact bone tissue are presented and compared with analogous investigation carried out on calcium and barium. The investigations were conducted using the isotopes 201Pb, 133Ba, 45Ca, with a small quantity of appropriate lead, barium or calcium carrier. The isotopes were administered to groups of rabbits of Chinchila strain (8 rabbits for 210Pb, 33 for 133Ba and 35 for 45Ca) in a single intravenous injection. The content of 210Pb, 133Ba, or 45Ca was determined in femoral and tibial bone shafts and in the plasma by radiochemical nethods. The results indicated that the addition rate of 210Pb into bone tissue from the plasma is about twice as high as the rate of 45Ca addition and it approximates the rate for 133Ba.
在这项工作中，展示了铅掺入致密骨组织速率的研究结果，并与对钙和钡进行的类似研究进行了比较。研究使用了同位素201Pb、133Ba、45Ca，并添加了少量适当的铅、钡或钙载体。将这些同位素通过单次静脉注射给予青紫蓝品系的兔群（210Pb组8只兔，133Ba组33只兔，45Ca组35只兔）。通过放射化学方法测定股骨和胫骨干以及血浆中210Pb、133Ba或45Ca的含量。结果表明，血浆中210Pb掺入骨组织的速率约为45Ca掺入速率的两倍，并且接近133Ba的掺入速率。
